Thursday, May 20, 2010

What book do you recomend me...?

I really like reading, but I don't have a lot of time to read. I like adventures and novels. Have you read "Flowers for Algernon" I loved it ,what other little book do you recomend?

What book do you recomend me...?
If you are a true reader then there are a number of books.


Five smooth Stones,A Time to Kill,Word of Honor,The First


Man in Rome,Fields of Fire,The complete works of John Jake's Bicentennial Series,79 Park Ave,The Quiet Game,The complete works of Ellswith thane.For the the romantic in you


There is Shanna.Rage of Angels,The Bourne Identity,The Betsy.Its so much easier to name authors.Jeffrey Archer


Sidney,Robert Ludlum,and Rosemary Rodgers.These are just some.I have a very large library.So if you need more info IM me.My books are in the 400 page range.ENJOY!
Reply:Ahem.... what was the last answer about??





Anyway, back to your question, I think you could try Jonathan Stroud. You may say he's a kid's author, but I like the writing, it's a lot more exciting than many others.





Try Rider Haggard- Solomon's Mines, She, many more. Go back to the classics- Treasure Island, Robinson Crusoe (NOT one of my favs) Swiss Family Robinson, Coral Island, many more. All adventures.
Reply:Julian Rathbone "Kings of Albion"


John Case "The Genesis Code"


Peter Ackroyd "The Hose of Doctor Dee"


Tim Powers "On Stranger Tides" and "The Anubis Gates"
Reply:Suspensions





Definition:


A pharmaceutical suspension is a type of disperse system in which one substance (the disperse phase) is distributed in particulate form throughout another (the continuous phase).





Classification:


Suspension may be classified into,


1) Coarse Suspension


2) Colloidal Suspension





1) Coarse suspension:


In which the particles are larger than 1 um (micrometer) in diameter.





2) Colloidal Suspension:


In which the particles may be considerably less then 1 um (micrometer) in diameter.





Formulation





Formulation include


1) Vehicle


2) Other Additives


1) Vehicle:


The vehicle is the medium in which the ingredients of a medicinal suspension are dispersed.





Vehicle may be


a) Aqueous


b) Non aqueous





a) Aqueous Vehicle:


For most of the pharmaceutical solution, water is usually the vehicle of choice. The density of an aqueous vehicle may be increased by adding glycerol or sucrose.





b) Non aqueous vehicle:


Non aqueous vehicles may be occasionally used for drugs that are unstable in the presence of water.


E.g. coconut oil





2) Other additives:


The additives that are included in pharmaceutical suspension are





a) Buffers:


Phosphate


Potassium





b) Stabilizers:


Ascorbic acid


Sodium Meta bisulphate





c) Preservatives:


Chloroform water


Benzoic acid


Chlorobutanol


Chlorocresol





d) Colours:


Nitrodyes


Nitrosodyes


Azodyes


Thiaxenes


Caramel


Burn sugar





e) Flavours:


Pineapple


Ginger


Orange


Rose


Lemon


Lavender


Jasmine


Cinnamon


Banana





f) Thickening agent:


i) polysacchrides:


Gum acacia


Tragacanth


Sodium alginate


Starch


Xanthene





ii) Water soluble cellulose:


Methyl cellulose


Hydroxyl ethyl cellulose


Sodium carboxymethyl -


-cellulose


Clays


Bentonite


Aluminium magnesium -


- silicate


Hectorite


Colloidal silicon dioxide

















Properties of a good pharmaceutical suspension:





• After shaking, the medicament stays in suspension long enough for a dose to be accurately measured.


• The suspension is easily removed from the container. I.e. it is pourable.


• The sediment formed on standing is bulky enough easily redispersed.


• The particles in suspension are small and relatively uniform in size so that the product is free from a gritty texture.








* Deflocculated suspension *





* In a completely deflocculated system all the particles remain separate as very small individual units and settling is therefore slow.


* The repulsion between particles prevents the formation of larger aggregates during sedimentation.


* However, the sediments that forms is eventually very hard to redisperse and is describe as a “cake “ or “ clay “


* Flocculated suspension *





* Flocculation involves the aggregation of individual small particles to form large groups, clumps, or floccules.


* Settling of these large aggregated particles is much faster than in the deflocculated state because its size is greater.


* The sediment formed is loose easily redispersible


* If excessive flocculation occurs particle trapped insides the floccules can cause the suspension to become very viscous and unpourable.


* flocculating agents include electrolytes, ionic surfactants, some polymer materials. eg, starch.








Compounding





The basic techniques for preparation for


pharmaceutical suspension are,





a) Weighing of raw material


b) Measuring of liquids


c) Size reduction and mixing


d) Filtration and dissolution





Dispensing





Include





a) Suspension as Oral dosage forms


i) Mixtures


b) Suspension for External use


i) Lotions


c) Suspension as “ Emergency “ formulations








a) Suspension for Oral dosage forms:





Advantages of Suspension as oral dosage form





* Suspended insoluble medicaments are easy to swallow.


* Insoluble derivatives in suspension may be more palatable than soluble derivatives in solution.


* Bulky insoluble powders, such as kaoline and chalk may be administered in suspension in order to act as a adsorbents of toxins or to reduce excessive acidity in gastrointestinal track.











Disadvantage of suspensions as oral dosage forms





* The preparation must be shaken prior to measuring a


dose


* Accuracy of dosage is less reliable than with solutions.


* Storage may lead to changes in the disperse system,


particularly if there are flocculations in temperature in temperature.





i) Mixtures:


Are liquid preparations for oral administration and contain medicaments dissolved or suspended in waster.





Shelf life for Mixtures:


Most official Mixtures have a relatively short life and should be recently or freshly prepared.


For ready made proprietary suspension’s the manufacturers literature should be consulted. Some proprietary suspensions are packed and stored as dry powders for reconstitution by the pharmacist immediately prior to issue to the patient. The reconstituted product usually has a short life after issue, diluted products also have a reduced shelf life usually a maximum of 14 days.





Containers for Mixtures:


Amber medicine bottle


A 5 ml measuring spoon should be supplied to the patient.





Special labels and advice for patients:
































b) Suspensions for External use:





i) Lotions:


Lotions containing suspended solids evaporate when applied to the skin leaving a light deposit of medicament on the surface. Suspensions made with some types of thickening agent, such as poly saccharide , leave fairly strong, non sticky film and gives protection.





Shelf life for lotions:


Long shelf life more than 1 year.





Container for Lotions:


Amber fluted bottles are used for extemporaneous prepared lotions. If the preparation is viscous a wide mouthed jar may be used





Special label and advice for patients:




















c) Suspension as emergency formulations:


In the absence of a commercially available liquid preparation the pharmacist is requested to prepare a liquid dosage form the commercial material. This usually involves crushing tablets or opening capsules to prepare a suspension.





Dispensing Assignment





Prepared by:





Urooj Fatima javed








Information about all the planets of the Solar System





Planet Distance Sun Dia m.


Kilo m. Period of revolution Period rotation Average temperature Moon


Mercury 58 4900 88 days 59 days -170 to 450oC 0


Venus 110 12100 225 days 243 days 480oC 0


Earth 150 12800 365 days 24 hours 22oC 1


Mars 228 6780 1 year 24 hours -30oC 2


Jupiter 780 142800 11 years 9 hours 150oC 16


Saturn 1430 120800 29 years 10 hours -180oC 24


Uranus 2870 51800 84 years 12 hours -210oC 15


Neptune 4497 49400 164 years 15 hours -220oC 8


Pluto 5909 5800 248 years 6 days -230oC 1











1) Mercury:


• Mercury is nearest star to the Sun in the solar system.


• It is made of solid rocks.


• It surface contains ditches like moon.





2) Venus:


• Venus is nearest star to the Solar System.


• There is no availability of Oxygen and water.


• Venus is the only planet which spin motion is opposite of the solar system.


• Its temperature is more than the temperature of Mercury.





3) Earth:


• Earth is the only planet which bears life.


• It contains water and oxygen.


• It has suitable temperature.








4) Mars:


• It is also called red planet.


• It is made of rocks.


• It contains carbon dioxide, nitrogen, oxygen, argon %26amp; vapours of water.





5) Jupiter:


• It is the biggest planet of the solar system.


• It contains hydrogen and helium gases.


• Jupiter is the huge ball of the gases.


• It contains ring around it.





6) Saturn:


• It is the second largest planet of the solar system.


• It is made of hydrogen and helium gases.


• It contains ring around it.





7) Uranus:


• It is the third largest planet of the solar system.


• It contains hydrogen and helium gases.


• It looks greenish due to methane gas (CH4).


• It contains ring around it.





8) Neptune:


• It is the fourth largest planet of the solar system.


• It contains hydrogen, methane %26amp; helium gases.


• Neptune is a big ball of water, ammonia %26amp; molten rocks.


• It contains ring around it.





9) Pluto:


• In the solar system, Pluto is the fartherest planet of the sun.


• Its path around the Sun is oblong %26amp; tilted.








Submitted to:





Mam Nosheen jawad











1st semester


3rd professional

















The Department of Pharmacy


The University of Faisalabad
Reply:Catcher in the Rye It's about the same length and the same level of reading. Pax - C.


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